Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Do not freeze topical estradiol. Keep estradiol gel away from open flame. Dispose of your estradiol gel pump after you have used 64 doses even if it is not completely empty.
Estradiol (Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs. It is available in multiple generic and brand versions.