Storage Instructions

Store at room temperature at 77 degrees F (25 degrees C). Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.

Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

Properly discard this product when it is expired or no longer needed.

Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.


Endometrin is a progesterone vaginal insert often prescribed for infertile women during the luteal phase of an Assisted Reproductive Technology (ART) treatment. Endometrin is indicated to support embryo implantation and early pregnancy by supplementing the needed progesterone support.

How to Use Endometrin

Here are step-by-step instructions for taking Cetrotide™ (cetrorelix) injections:

  1. Cetrotide™ is injected subcutaneously—or into the fatty tissue under your skin. The primary sites for injection are your abdomen—2 inches on either side of the navel, and your upper, outer-thigh where the skin is loose. Wash your hands thoroughly and make sure that the surface you work on is clean.
    2 Flip off the plastic cover of the vial and wipe the rubber stopper with an alcohol swab.
  2. Put the injection needle with the yellow mark (20 gauge) on the pre-filled syringe.
  3. Push the needle through the rubber stopper of the vial and slowly inject the solvent into the vial. Leaving the syringe in the vial, gently swirl the vial until the solution is clear. Avoid making bubbles. Do not shake.
  4. Invert the vial and pull back the needle as far as needed to withdraw all of the liquid in the vial. You might not be able to withdraw every drop.
  5. Replace the yellow marked needle with the (27 gauge) ½ inch syringe.
  6. With the needle pointing toward the ceiling, flick the side of the syringe to disperse any air bubbles and the air pocket at the top of the syringe, then gently push the plunger until one or two drops of liquid are expressed to make sure you have eliminated any air.
  7. Gently push on plunger until air pocket is gone and expel a drop of liquid
Instructional Video